One concern about anabolic steroids is the inhibition of natural testosterone
production. This inhibition is inevitable in the anabolic steroid cycle.
However, prolonged postcyclical inhibition can lead to loss of gains and may
lead to adverse side effects, such as depression and loss of libido. In
contrast, where natural testosterone secretion recovers rapidly, adverse effects
on mood or libido can be reduced or eliminated, and benefits are maintained
well. Posterior circulation therapy (PCT) with Nolvadex is specifically
introduced to enable faster recovery.
To understand how Nolvadex accelerates recovery, it is important to understand
how inhibition occurs and how it is reversed by selective estrogen receptor
modulators (SERMs), such as Nolvadex.
The production of testosterone is regulated in a chain process. The testes
produce testosterone according to the amount of LH produced by the pituitary
gland. The pituitary gland produces LHRH according to the amount of LHRH
produced by the hypothalamus and other factors. The hypothalamus produces LHRH
based on the levels of estrogen and androgen in the blood and other factors.
In this process, estradiol is usually the most important estrogen, testosterone
is the most important androgen, but in the anabolic steroid cycle, androgen may
be any anabolic steroid.
At present, we assume that the ratio of testosterone to estradiol is fixed in
individuals. This is usually true because estradiol is produced from
testosterone. When we look at this, we think that when testosterone goes up or
down, estradiol goes up or down.
Under normal circumstances, without the use of anabolic steroids, this process
will keep testosterone and estradiol in the normal range of balance. If they are
relatively high for individuals in a short period of time, the production of
LHRH and LH will be reduced, thus reducing the production of testosterone and
normalizing the level.
If estradiol levels are low, or rather, estrogen receptor activity is low, the
hypothalamus produces more LHRH. This produces more luteinizing hormone and more
What happens to the anabolic steroid cycle? Here, the hypothalamus always feels
abnormally high androgen and may also feel abnormally high estrogen. So, it
stops LH production, so does testosterone production.
Again, it's inevitable, and it's not necessarily a problem in itself.
But what about the post cycle? Shouldn't luteinizing hormone be restored
immediately after a drop in androgen levels by injection or oral administration?
Androgen suppression will end.
Unfortunately, this usually doesn't happen. As mentioned above, in addition to
the current androgen and estrogen levels, there are other factors involved in
the regulation of LHRH and LH production. Androgen and estrogen levels in the
first few weeks are also important. After exposure to steroid cycles, the
reduction of androgen and estrogen levels to normal levels may not in itself be
sufficient to restart LH production, even if estradiol levels are normal.
Now - finally! It's a place for novadex.
By occupying the binding sites of estrogen receptors in cells without activating
them, novaks prevents these receptors from being activated by estradiol. The
cells then "think" that estradiol levels are low and respond accordingly.
In the case of the hypothalamus, it produces more LHRH in response to
significantly lower estrogen levels. This stimulates the pituitary gland to
produce LH, which in turn stimulates the testes and restores testosterone
There are several proven Nolvadex PCT dose regimens.
All good protocols start with a higher dose and then continue with a low dose of
20 mg / day. The reason is that when a drug is taken, the amount in the body is
not only the amount just taken, but also the amount accumulated from the
previous dose for about 6 days. At the beginning of use, this accumulation does
not exist and will not have any effect unless this is taken into account. If
it's not included, it takes weeks to build up.
One way to correct this is to take 120 mg on the first day and 40 mg in three
doses. This will quickly bring the concentration to roughly the same level as
that achieved at a daily dose of 20 mg. After that, the dose was the standard 20
mg / day.
Another way to get the right level quickly is to use double doses for a limited
period of time. I suggest writing only four days, because that's all you need,
but many authors suggest two weeks. (this, however, goes beyond the level of 20
mg per day.)
The drug should be continued until the production of natural testosterone is
fully restored. It is reasonable to plan for 30 days.
Must realize that using more Nolvadex than above does not produce better
results. There is absolutely no reason for you to go beyond my advice. This will
only aggravate the side effects.
Even at the right dose, side effects may include impaired vision and decreased
libido. In case of visual impairment, Nolvadex should be stopped immediately and
anti aromatase, such as arimeadex or letrozole, should be used instead.
If libido declines, the problem is only temporary. Clomid may serve as an
alternative to SERM in the future, as it may be more advantageous in this
There is usually no reason to combine SERMs: for example, usually clomid or
Nolvadex should be used as the only SERM, not together. However, in some
difficult cases, the use of both clomid and Nolvadex is beneficial, but at half
of each dose. In the hypothalamus, clomid alone, Nolvadex alone, or both may
have no difference in half dose, but in pituitary, clomid and Nolvadex have
opposite effects, so the combination of clomid and Nolvadex is different. (in
some cases, I learned the benefits of combining from Dr. Scully.)
Before the advent of cheap anti_aromatase, nolvadex was also very popular as a
drug against female breast hypertrophy. Today, it is best to use anti aromatase
as a preventative, but if gynecological symptoms suddenly occur during the
menstrual cycle, immediate treatment with Nolvadex will help. The dose for this
use is the same as PCT.
This product was added to our catalog on Sunday 02 August, 2020.